首页> SLAS discovery : advancing life sciences R & D> Protocol for 3D drug sensitivity and resistance testing of patient-derived cancer cells in 384-well plates.

Protocol for 3D drug sensitivity and resistance testing of patient-derived cancer cells in 384-well plates.

导出 LinkOut

翻译打印收藏纠错

第一作者： Michaela,Feodoroff

第一单位： Institute for Molecular Medicine Finland (FIMM), Helsinki Institute for Life Sciences (HiLIFE), University of Helsinki, Helsinki, Finland; Laboratory of Immunovirotherapy, Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program (TRIMM), University of Helsinki, Helsinki, Finland; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.

作者： Michaela,Feodoroff ^[1] ; Piia,Mikkonen ^[2] ; Mariliina,Arjama ^[3] ; Astrid,Murumägi ^[3] ; Olli,Kallioniemi ^[4] ; Swapnil,Potdar ^[3] ; Laura,Turunen ^[3] ; Vilja,Pietiäinen ^[5]

作者单位： Institute for Molecular Medicine Finland (FIMM), Helsinki Institute for Life Sciences (HiLIFE), University of Helsinki, Helsinki, Finland; Laboratory of Immunovirotherapy, Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program (TRIMM), University of Helsinki, Helsinki, Finland; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland. ^[1] Institute for Molecular Medicine Finland (FIMM), Helsinki Institute for Life Sciences (HiLIFE), University of Helsinki, Helsinki, Finland; UPM-Kymmene Corporation, UPM Biomedicals, Helsinki, Finland. ^[2] Institute for Molecular Medicine Finland (FIMM), Helsinki Institute for Life Sciences (HiLIFE), University of Helsinki, Helsinki, Finland. ^[3] Institute for Molecular Medicine Finland (FIMM), Helsinki Institute for Life Sciences (HiLIFE), University of Helsinki, Helsinki, Finland; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland; Science for Life Laboratory (SciLifeLab), Department of Oncology and Pathology, Karolinska Institutet, Solna, Sweden. ^[4] Institute for Molecular Medicine Finland (FIMM), Helsinki Institute for Life Sciences (HiLIFE), University of Helsinki, Helsinki, Finland; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland. Electronic address: vilja.pietiainen@helsinki.fi. ^[5]

关键词 3D cell culture 3D matrix Drug sensitivity and resistance testing Functional precision medicine Organoids Patient-derived (cancer) cells Spheroids

医学主题词人类(Humans);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);药物发现(Drug Discovery);肿瘤(Neoplasms);胶原(Collagen)

DOI 10.1016/j.slasd.2022.11.003

PMID 36464160

发布时间 2023-03-27

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交