首页> Journal of the American Chemical Society> An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4.

An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4.

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第一作者： Angel,Gonzalez-Valero

第一单位： Department of Chemistry, University of California, Berkeley, California 94720, United States.

作者： Angel,Gonzalez-Valero ^[1] ; Audrey G,Reeves ^[1] ; Annika C S,Page ^[1] ; Patrick J,Moon ^[1] ; Edward,Miller ^[1] ; Katia,Coulonval ^[2] ; Steven W M,Crossley ^[1] ; Xiao,Xie ^[1] ; Dan,He ^[1] ; Patricia Z,Musacchio ^[1] ; Alec H,Christian ^[1] ; Jeffrey M,McKenna ^[3] ; Richard A,Lewis ^[3] ; Eric,Fang ^[3] ; Dustin,Dovala ^[3] ; Yipin,Lu ^[3] ; Lynn M,McGregor ^[3] ; Markus,Schirle ^[3] ; John A,Tallarico ^[3] ; Pierre P,Roger ^[2] ; F Dean,Toste ^[1] ; Christopher J,Chang ^[4]

作者单位： Department of Chemistry, University of California, Berkeley, California 94720, United States. ^[1] Faculté de Médecine, Institute of Interdisciplinary Research, Université Libre de Bruxelles, Campus Erasme, Brussels 1070, Belgium. ^[2] Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States. ^[3] Department of Chemistry, University of California, Berkeley, California 94720, United States.;Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, United States. ^[4]