Single-cell profiles reveal tumor cell heterogeneity and immunosuppressive microenvironment in Waldenström macroglobulinemia.

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第一作者： Hao,Sun

第一单位： State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China.;Tianjin Institutes of Health Science, Tianjin, 301600, China.

作者： Hao,Sun ^[1] ; Teng,Fang ^[1] ; Tingyu,Wang ^[2] ; Zhen,Yu ^[1] ; Lixin,Gong ^[1] ; Xiaojing,Wei ^[2] ; Huijun,Wang ^[2] ; Yi,He ^[2] ; Lanting,Liu ^[1] ; Yuting,Yan ^[2] ; Weiwei,Sui ^[2] ; Yan,Xu ^[2] ; Shuhua,Yi ^[2] ; Lugui,Qiu ^[3] ; Mu,Hao ^[4]

作者单位： State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China.;Tianjin Institutes of Health Science, Tianjin, 301600, China. ^[1] State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China. ^[2] State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China. qiulg@ihcams.ac.cn.;Tianjin Institutes of Health Science, Tianjin, 301600, China. qiulg@ihcams.ac.cn. ^[3] State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China. haomu@ihcams.ac.cn.;Tianjin Institutes of Health Science, Tianjin, 301600, China. haomu@ihcams.ac.cn. ^[4]

关键词 Cancer microenvironment Immunotherapy Tumor cell heterogeneity Waldenstr?m macroglobulinemia

主题词人类(Humans);生态系统(Ecosystem);Waldenstrom巨球蛋白血症(Waldenstrom Macroglobulinemia);骨髓(Bone Marrow);肿瘤微环境(Tumor Microenvironment);B-淋巴细胞(B-Lymphocytes)

DOI 10.1186/s12967-022-03798-6

PMID 36494694

发布时间 2024-09-08

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