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Heterozygous GABA<sub>A</sub> receptor β3 subunit N110D knock-in mice have epileptic spasms.

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第一作者： Shimian,Qu

第一单位： Department of Neurology, Meharry Medical College, Nashville, Tennessee, USA.

作者： Shimian,Qu ^[1] ; Laurel G,Jackson ^[2] ; Chengwen,Zhou ^[1] ; DingDing,Shen ^[2] ; Wangzhen,Shen ^[1] ; Gerald,Nwosu ^[3] ; Rachel,Howe ^[1] ; Mackenzie A,Catron ^[2] ; Carson,Flamm ^[1] ; Marshall,Biven ^[1] ; Jing-Qiong,Kang ^[4] ; Robert L,Macdonald ^[5]

作者单位： Department of Neurology, Meharry Medical College, Nashville, Tennessee, USA. ^[1] Department of Neurology, Meharry Medical College, Nashville, Tennessee, USA.;Department of Program in Neuroscience, Meharry Medical College, Nashville, Tennessee, USA. ^[2] Department of Neurology, Meharry Medical College, Nashville, Tennessee, USA.;Department of Program in Neuroscience, Meharry Medical College, Nashville, Tennessee, USA.;Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, Nashville, Tennessee, USA. ^[3] Department of Neurology, Meharry Medical College, Nashville, Tennessee, USA.;Department of Pharmacology, Meharry Medical College, Nashville, Tennessee, USA.;Vanderbilt Kennedy Center of Human Development, Vanderbilt University, Nashville, Tennessee, USA. ^[4] Department of Neurology, Meharry Medical College, Nashville, Tennessee, USA.;Department of Pharmacology, Meharry Medical College, Nashville, Tennessee, USA.;Department of Molecular Physiology and Biophysics, Meharry Medical College, Nashville, Tennessee, USA. ^[5]

关键词 GABRB3 animal modelsepileptic encephalopathy infantile spasms syndrome thalamocortical circuits