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Distinct hypothalamic involvement in the amyotrophic lateral sclerosis-frontotemporal dementia spectrum.

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第一作者： Nga Yan,Tse

第一单位： The University of Sydney, Brain & Mind Centre, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia.

作者： Nga Yan,Tse ^[1] ; Martina,Bocchetta ^[2] ; Emily G,Todd ^[2] ; Emma M,Devenney ^[1] ; Sicong,Tu ^[1] ; Jashelle,Caga ^[1] ; John R,Hodges ^[3] ; Glenda M,Halliday ^[4] ; Muireann,Irish ^[5] ; Matthew C,Kiernan ^[6] ; Olivier,Piguet ^[5] ; Jonathan D,Rohrer ^[2] ; Rebekah M,Ahmed ^[7]

作者单位： The University of Sydney, Brain & Mind Centre, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia. ^[1] Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom. ^[2] The University of Sydney, Brain & Mind Centre, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The University of Sydney, School of Psychology and Brain & Mind Centre, Sydney, Australia. ^[3] The University of Sydney, Sydney Medical School and Brain & Mind Centre, Sydney, Australia. ^[4] The University of Sydney, School of Psychology and Brain & Mind Centre, Sydney, Australia. ^[5] The University of Sydney, Brain & Mind Centre, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The University of Sydney, Sydney Medical School and Brain & Mind Centre, Sydney, Australia. ^[6] The University of Sydney, Brain & Mind Centre, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; Memory and Cognition Clinic, Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, Australia. Electronic address: Rebekah.ahmed@sydney.edu.au. ^[7]

关键词 Amyotrophic lateral sclerosis Cognitive and behavioural impairment Frontotemporal dementia Hypothalamus Neuroimaging Neuropathophysiology

主题词人类(Humans);额颞叶痴呆(Frontotemporal Dementia);肌萎缩侧索硬化(Amyotrophic Lateral Sclerosis);情感淡漠(Apathy);摄食行为(Feeding Behavior);下丘脑(Hypothalamus)

DOI 10.1016/j.nicl.2022.103281

PMID 36495857

发布时间 2025-05-30

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