Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice.

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作者： Jimin,Kim ^[1] ; Seul Ki,Lee ^[1] ; Minyoung,Jung ^[1] ; Seon-Yeong,Jeong ^[1] ; Haedeun,You ^[1] ; Ji-Yeon,Won ^[1] ; Sang-Deok,Han ^[1] ; Hye Jin,Cho ^[1] ; Somi,Park ^[1] ; Joonghoon,Park ^[2] ; Tae Min,Kim ^[3] ; Soo,Kim ^[4]

作者单位： Brexogen Research Center, Brexogen Inc., Songpa-Gu, Seoul, 05855, South Korea. ^[1] Graduate School of International Agricultural Technology, Seoul National University, Pyeongchang, Gangwon-do, 25354, South Korea. ^[2] Institutes of Green-Bio Science and Technology, Seoul National University, Pyeongchang, Gangwon-do, 25354, South Korea. ^[3] Graduate School of International Agricultural Technology, Seoul National University, Pyeongchang, Gangwon-do, 25354, South Korea. taemin21@snu.ac.kr. ^[4] Institutes of Green-Bio Science and Technology, Seoul National University, Pyeongchang, Gangwon-do, 25354, South Korea. taemin21@snu.ac.kr. ^[5] Brexogen Research Center, Brexogen Inc., Songpa-Gu, Seoul, 05855, South Korea. sue.kim@brexogen.com. ^[6]

关键词 Atopic dermatitis Extracellular vesicles IFN-γ iPSC-derived MSC

主题词小鼠(Mice);动物(Animals);皮炎, 特应性(Dermatitis, Atopic);间质干细胞(Mesenchymal Stem Cells);细胞因子类(Cytokines);表皮(Epidermis);干扰素γ(Interferon-gamma)

DOI 10.1186/s12951-022-01728-8

PMID 36496385

发布时间 2022-12-20

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