首页> International journal of molecular sciences> Tolerogenic Dendritic Cells Induce Apoptosis-Independent T Cell Hyporesponsiveness of SARS-CoV-2-Specific T Cells in an Antigen-Specific Manner.

Tolerogenic Dendritic Cells Induce Apoptosis-Independent T Cell Hyporesponsiveness of SARS-CoV-2-Specific T Cells in an Antigen-Specific Manner.

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第一作者： Mats,Van Delen

第一单位： Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.

作者： Mats,Van Delen ^[1] ; Ibo,Janssens ^[1] ; Amber,Dams ^[1] ; Laurence,Roosens ^[2] ; Benson,Ogunjimi ^[3] ; Zwi N,Berneman ^[4] ; Judith,Derdelinckx ^[5] ; Nathalie,Cools ^[4]

作者单位： Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium. ^[1] Laboratory of Clinical Biology, Antwerp University Hospital, 2650 Edegem, Belgium. ^[2] Centre for Health Economics Research & Modeling Infectious Diseases (CHERMID), VAXINFECTIO, University of Antwerp, 2610 Antwerp, Belgium.;Department of Paediatrics, Antwerp University Hospital, 2650 Edegem, Belgium.;Antwerp Center for Translational Immunology and Virology (ACTIV), VAXINFECTIO, University of Antwerp, 2610 Antwerp, Belgium.;Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, 2020 Antwerp, Belgium. ^[3] Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.;Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, 2650 Edegem, Belgium. ^[4] Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.;Department of Neurology, Antwerp University Hospital, 2650 Edegem, Belgium. ^[5]

关键词 T cell apoptosis antigen specificity severe COVID-19 tolerance tolerogenic dendritic cells

医学主题词人类(Humans);T淋巴细胞(T-Lymphocytes);免疫耐受(Immune Tolerance);树突细胞(Dendritic Cells);抗原(Antigens);肽类(Peptides);细胞凋亡(Apoptosis)

DOI 10.3390/ijms232315201

PMID 36499533

发布时间 2024-10-05

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