iPSC-based model of Vogt-Koyanagi-Harada disease for phenotype recapitulation and drug screening.

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第一作者： Wanqian,Li

第一单位： The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Ophthalmology, Chongqing, China; Chongqing Eye Institute, Chongqing, China; Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, Chongqing, China.

作者： Wanqian,Li ^[1] ; Jun,Tan ^[1] ; Siyuan,He ^[1] ; Yingying,Yue ^[1] ; Huan,Liu ^[1] ; Ruonan,Li ^[1] ; Xiaotang,Wang ^[1] ; Guoqing,Wang ^[1] ; Wei,Fan ^[1] ; Chenyang,Zhao ^[1] ; Qian,Zhou ^[1] ; Peizeng,Yang ^[2] ; Shengping,Hou ^[3]

作者单位： The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Ophthalmology, Chongqing, China; Chongqing Eye Institute, Chongqing, China; Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, Chongqing, China. ^[1] The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Ophthalmology, Chongqing, China; Chongqing Eye Institute, Chongqing, China; Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, Chongqing, China.. Electronic address: peizengycmu@126.com. ^[2] The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Ophthalmology, Chongqing, China; Chongqing Eye Institute, Chongqing, China; Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, Chongqing, China.. Electronic address: sphou828@163.com. ^[3]

关键词 Drug screening Early growth response gene 2 (EGR2)Induced pluripotent stem cells (iPSCs)Retinal pigment epithelium (RPE)Vogt-Koyanagi-Harada (VKH) disease

主题词人类(Humans);葡萄膜脑膜脑炎综合征(Uveomeningoencephalitic Syndrome);诱导多能干细胞(Induced Pluripotent Stem Cells);药物评价, 临床前(Drug Evaluation, Preclinical);白细胞, 单核(Leukocytes, Mononuclear);视网膜色素上皮(Retinal Pigment Epithelium)

DOI 10.1016/j.clim.2022.109205

PMID 36509389

发布时间 2023-02-12

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准确一般字义偏差语意偏离译文作用小提交