Enhancement of T cell infiltration <i>via</i> tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors.

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第一作者： Tao,Chen

第一单位： Orthopaedic Oncology Services, Department of Orthopaedics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009, China.

作者： Tao,Chen ^[1] ; Yucheng,Xue ^[2] ; Shengdong,Wang ^[3] ; Jinwei,Lu ^[1] ; Hao,Zhou ^[2] ; Wenkan,Zhang ^[3] ; Zhiyi,Zhou ^[1] ; Binghao,Li ^[2] ; Yong,Li ^[3] ; Zenan,Wang ^[1] ; Changwei,Li ^[2] ; Yinwang,Eloy ^[3] ; Hangxiang,Sun ^[1] ; Yihang,Shen ^[2] ; Mohamed Diaty,Diarra ^[3] ; Chang,Ge ^[1] ; Xupeng,Chai ^[2] ; Haochen,Mou ^[3] ; Peng,Lin ^[4] ; Xiaohua,Yu ^[1] ; Zhaoming,Ye ^[2]

作者单位： Orthopaedic Oncology Services, Department of Orthopaedics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009, China. ^[1] Orthopaedic Research Institute, Zhejiang University, Hangzhou, 310009, China. ^[2] Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province, Hangzhou, 310009, China. ^[3] The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, 310009, China. ^[4] Qingtian People's Hospital, Department of Orthopedics, Lishui, 323900, China. ^[5] Department of Orthopedics, Shanghai Key Laboratory for the Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 20025, China. ^[6] Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China. ^[7]

关键词 Adoptive cell therapy (ACT)Cell surface engineering Phage display Solid tumor Th9 cell

DOI 10.1016/j.bioactmat.2022.11.022

PMID 36514387

发布时间 2022-12-21

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2023年23卷

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Enhancement of T cell infiltration <i>via</i> tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors.

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Enhancement of T cell infiltration <i>via</i> tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors.

Bioactive materials

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Bioactive materials

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