Higher circulating Trimethylamine N-oxide levels are associated with worse severity and prognosis in pulmonary hypertension: a cohort study.

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作者： Yicheng,Yang ^[1] ; Beilan,Yang ^[1] ; Xin,Li ^[1] ; Lin,Xue ^[1] ; Bingyang,Liu ^[1] ; Yanru,Liang ^[1] ; Zhihui,Zhao ^[1] ; Qin,Luo ^[1] ; Zhihong,Liu ^[1] ; Qixian,Zeng ^[2] ; Changming,Xiong ^[3]

作者单位： Center of Respiratory and Pulmonary Vascular Disease, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 North Lishi Road, Xicheng District, Beijing, 100037, China. ^[1] Center of Respiratory and Pulmonary Vascular Disease, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 North Lishi Road, Xicheng District, Beijing, 100037, China. zengqixian@fuwaihospital.org. ^[2] Center of Respiratory and Pulmonary Vascular Disease, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 North Lishi Road, Xicheng District, Beijing, 100037, China. xiongcmfw@163.com. ^[3]

关键词 Biomarker Cardiovascular diseases Prognosis Pulmonary hypertension Trimethylamine N-oxide

主题词人类(Humans);队列研究(Cohort Studies);高血压, 肺性(Hypertension, Pulmonary);危险因素(Risk Factors);预后(Prognosis)

DOI 10.1186/s12931-022-02282-5

PMID 36517838

发布时间 2022-12-22

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