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Structural basis of the acyl-transfer mechanism of human GPAT1.

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第一作者： Zachary Lee,Johnson

第一单位： Discovery Sciences, Medicine Design, Pfizer Inc., Groton, CT, USA.

作者： Zachary Lee,Johnson ^[1] ; Mark,Ammirati ^[1] ; David Jonathan,Wasilko ^[1] ; Jeanne S,Chang ^[1] ; Stephen,Noell ^[1] ; Timothy L,Foley ^[1] ; Hyejin,Yoon ^[2] ; Kathleen,Smith ^[2] ; Shoh,Asano ^[2] ; Katherine,Hales ^[2] ; Min,Wan ^[2] ; Qingyi,Yang ^[3] ; Mary A,Piotrowski ^[1] ; Kathleen A,Farley ^[1] ; Tamara,Gilbert ^[2] ; Lisa M,Aschenbrenner ^[1] ; Kimberly F,Fennell ^[1] ; Jason K,Dutra ^[4] ; Mary,Xu ^[1] ; Chunyang,Guo ^[1] ; Alison E,Varghese ^[1] ; Justin,Bellenger ^[1] ; Alandra,Quinn ^[1] ; Christopher W,Am Ende ^[4] ; Graham M,West ^[1] ; Matthew C,Griffor ^[1] ; Donald,Bennett ^[5] ; Matthew,Calabrese ^[1] ; Claire M,Steppan ^[1] ; Seungil,Han ^[1] ; Huixian,Wu ^[6]

作者单位： Discovery Sciences, Medicine Design, Pfizer Inc., Groton, CT, USA. ^[1] Internal Medicine Research Unit, Pfizer Inc., Cambridge, MA, USA. ^[2] Internal Medicine, Medicine Design, Pfizer Inc., Cambridge, MA, USA. ^[3] Internal Medicine, Medicine Design, Pfizer Inc., Groton, CT, USA. ^[4] Biostatistics, Early Clinical Development, Pfizer Inc., Cambridge, MA, USA. ^[5] Discovery Sciences, Medicine Design, Pfizer Inc., Groton, CT, USA. huixian.wu@pfizer.com. ^[6]

医学主题词人类(Humans);肝(Liver);线粒体膜(Mitochondrial Membranes);甘油-3-磷酸O-酰基转移酶(Glycerol-3-Phosphate O-Acyltransferase);氨基酸序列(Amino Acid Sequence)

DOI 10.1038/s41594-022-00884-7

PMID 36522428

发布时间 2023-03-10

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