Combined proteomics and single cell RNA-sequencing analysis to identify biomarkers of disease diagnosis and disease exacerbation for systemic lupus erythematosus.

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第一作者： Yixi,Li

第一单位： Institute of Nephrology and Blood Purification, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.

作者： Yixi,Li ^[1] ; Chiyu,Ma ^[2] ; Shengyou,Liao ^[2] ; Suwen,Qi ^[2] ; Shuhui,Meng ^[2] ; Wanxia,Cai ^[2] ; Weier,Dai ^[2] ; Rui,Cao ^[3] ; Xiangnan,Dong ^[1] ; Bernhard K,Krämer ^[1] ; Chen,Yun ^[4] ; Berthold,Hocher ^[5] ; Xiaoping,Hong ^[4] ; Dongzhou,Liu ^[6] ; Donge,Tang ^[7] ; Jingquan,He ^[8] ; Lianghong,Yin ^[9] ; Yong,Dai ^[9]

作者单位： Institute of Nephrology and Blood Purification, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China. ^[1] Clinical Medical Research Center, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Jinan University, Shenzhen, China. ^[2] College of Natural Science, University of Texas at Austin, Austin, TX, United States. ^[3] Fifth Department of Medicine, University Medical Centre Mannheim, University of Heidelberg, Heidelberg, Germany. ^[4] Department of Nephrology, Charité-Universitätsmedizin Berlin, Berlin, Germany. ^[5] Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha, China. ^[6] Reproductive and Genetic Hospital of China International Trust and Investment Corporation (CITIC)-Xiangya, Changsha, China. ^[7] Institute of Medical Diagnostics (IMD), Berlin, Germany. ^[8] Department of Rheumatology and Immunology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Jinan University, Shenzhen, China. ^[9] Guangzhou Enttxs Medical Products Co., Ltd, Guangzhou, Guangzhou, China. ^[10]

关键词 biomarker disease diagnosis disease exacerbation immune cell machine learning