Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior.

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第一作者： Yang,He

第一单位： USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

作者： Yang,He ^[1] ; Bas,Brouwers ^[2] ; Hesong,Liu ^[1] ; Hailan,Liu ^[1] ; Katherine,Lawler ^[2] ; Edson,Mendes de Oliveira ^[2] ; Dong-Kee,Lee ^[3] ; Yongjie,Yang ^[1] ; Aaron R,Cox ^[4] ; Julia M,Keogh ^[2] ; Elana,Henning ^[2] ; Rebecca,Bounds ^[2] ; Aliki,Perdikari ^[2] ; Vikram,Ayinampudi ^[2] ; Chunmei,Wang ^[1] ; Meng,Yu ^[1] ; Longlong,Tu ^[1] ; Nan,Zhang ^[1] ; Na,Yin ^[1] ; Junying,Han ^[1] ; Nikolas A,Scarcelli ^[1] ; Zili,Yan ^[1] ; Kristine M,Conde ^[1] ; Camille,Potts ^[1] ; Jonathan C,Bean ^[1] ; Mengjie,Wang ^[1] ; Sean M,Hartig ^[3] ; Lan,Liao ^[4] ; Jianming,Xu ^[3] ; Inês,Barroso ^[3] ; Jacek,Mokrosinski ^[5] ; Yong,Xu ^[2] ; I,Sadaf Farooqi ^[6]

作者单位： USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA. ^[1] University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. ^[2] Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. ^[3] Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. ^[4] Exeter Centre of Excellence for Diabetes Research (EXCEED), University of Exeter Medical School, Exeter, UK. ^[5] USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA. yongx@bcm.edu. ^[6] Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. yongx@bcm.edu. ^[7] University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. isf20@cam.ac.uk. ^[8]