Functional and Taxonomic Traits of the Gut Microbiota in Type 1 Diabetes Children at the Onset: A Metaproteomic Study.

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第一作者： Stefano,Levi Mortera

第一单位： Unit of Human Microbiome, Multimodal Laboratory Medicine Research Area, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.

作者： Stefano,Levi Mortera ^[1] ; Valeria,Marzano ^[1] ; Pamela,Vernocchi ^[1] ; Maria Cristina,Matteoli ^[2] ; Valerio,Guarrasi ^[3] ; Simone,Gardini ^[3] ; Federica,Del Chierico ^[1] ; Novella,Rapini ^[2] ; Annalisa,Deodati ^[2] ; Alessandra,Fierabracci ^[4] ; Stefano,Cianfarani ^[5] ; Lorenza,Putignani ^[6]

作者单位： Unit of Human Microbiome, Multimodal Laboratory Medicine Research Area, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy. ^[1] Diabetes & Growth Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy. ^[2] GenomeUp SRL, 00165 Rome, Italy. ^[3] Infectivology and Clinical Trials Research Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy. ^[4] Diabetes & Growth Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.;Department of Systems Medicine, University of "Tor Vergata", 00133 Rome, Italy.;Department of Women's and Children Health, Karolisnska Institute, University Hospital, 17177 Stockholm, Sweden. ^[5] Unit of Human Microbiome, Multimodal Laboratory Medicine Research Area, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.;Unit of Microbiology and Diagnostic Immunology, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.;Unit of Human Microbiome, Department of Diagnostics and Laboratory Medicine, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy. ^[6]

关键词 Type 1 diabetes functional annotation gut microbiota insulin need label-free quantitative analysis (LFQ)metaproteomics paediatric