Comparative RNA-Sequencing Analysis Reveals High Complexity and Heterogeneity of Transcriptomic and Immune Profiles in Hepatocellular Carcinoma Tumors of Viral (HBV, HCV) and Non-Viral Etiology.

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作者： Liliana,Paslaru ^[1] ; Gabriela,Bindea ^[2] ; Anca,Nastase ^[3] ; Andrei,Sorop ^[4] ; Cristian,Zimbru ^[1] ; Vlad,Herlea ^[1] ; Doina,Hrehoret ^[5] ; Vlad,Brasoveanu ^[1] ; Radu,Zamfir ^[1] ; Simona,Dima ^[1] ; Irinel,Popescu ^[1]

作者单位： Fundeni Clinical Institute, 022328 Bucharest, Romania. ^[1] Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratory of Integrative Cancer Immunology, 75006 Paris, France. ^[2] Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, 75006 Paris, France. ^[3] Equipe Labellisée Ligue Contre le Cancer, 75006 Paris, France. ^[4] Department of Automation and Applied Informatics, Politehnica University Timisoara, 300223 Timisoara, Romania. ^[5]

关键词 HBV HCV RNA-seq biomarkers hepatocellular carcinoma immune infiltrate

主题词男(雄)性(Male);人类(Humans);癌, 肝细胞(Carcinoma, Hepatocellular);肝肿瘤(Liver Neoplasms);乙型肝炎病毒(Hepatitis B virus);丙型肝炎(Hepatitis C);RNA(RNA)

DOI 10.3390/medicina58121803

PMID 36557005

发布时间 2023-03-08

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