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首页> Viruses> Histone Deacetylase Inhibitor Panobinostat Benefits the Therapeutic Efficacy of Oncolytic Herpes Simplex Virus Combined with PD-1/PD-L1 Blocking in Glioma and Squamous Cell Carcinoma Models.

Histone Deacetylase Inhibitor Panobinostat Benefits the Therapeutic Efficacy of Oncolytic Herpes Simplex Virus Combined with PD-1/PD-L1 Blocking in Glioma and Squamous Cell Carcinoma Models.

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作者： Yinglin,Wu ^[1] ; Xiaoqing,Chen ^[2] ; Lei,Wang ^[2] ; Xusha,Zhou ^[3] ; Yonghong,Liu ^[2] ; Dongmei,Ji ^[2] ; Peigen,Ren ^[4] ; Grace Guoying,Zhou ^[3] ; Jing,Zhao ^[2]

作者单位： Department of Immunology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China. ^[1] Shenzhen International Institute for Biomedical Research, Shenzhen 518110, China. ^[2] Research Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. ^[3] Department of Medical Oncology, Shanghai Cancer Center and Shanghai Medical College, Fudan University, Shanghai 200032, China. ^[4]

关键词 HDACi panobinostat glioma oHSV squamous cell carcinoma

主题词人类(Humans);动物(Animals);小鼠(Mice);单纯疱疹病毒属(Simplexvirus);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);细胞系, 肿瘤(Cell Line, Tumor);神经胶质瘤(Glioma);溶瘤病毒(Oncolytic Viruses);癌, 鳞状细胞(Carcinoma, Squamous Cell);溶瘤病毒疗法(Oncolytic Virotherapy)

DOI 10.3390/v14122796

PMID 36560800

发布时间 2023-01-31

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2022年14卷12期

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