Design and synthesis of novel halogen rich salicylanilides as potential antileishmanial agents.

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作者： Jhajan,Lal ^[1] ; Karthik,Ramalingam ^[2] ; Rachana,Meena ^[1] ; Shabina B,Ansari ^[1] ; Deepanshi,Saxena ^[3] ; Sidharth,Chopra ^[4] ; Neena,Goyal ^[5] ; Damodara N,Reddy ^[6]

作者单位： Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Sector 10, Janakipuram Extension, Sitapur Road, Lucknow, 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India. ^[1] Division of Biochemistry and Structural Biology, CSIR-Central Drug Research Institute, Sector 10, Janakipuram Extension, Sitapur Road, Lucknow, 226031, India. ^[2] Division of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Sector 10, Janakipuram Extension, Sitapur Road, Lucknow, 226031, India. ^[3] Division of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Sector 10, Janakipuram Extension, Sitapur Road, Lucknow, 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India. ^[4] Division of Biochemistry and Structural Biology, CSIR-Central Drug Research Institute, Sector 10, Janakipuram Extension, Sitapur Road, Lucknow, 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India. Electronic address: neena_goyal@cdri.res.in. ^[5] Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Sector 10, Janakipuram Extension, Sitapur Road, Lucknow, 226031, India; Academy of Scientific and Innovative Research, Ghaziabad, 201002, India. Electronic address: damodara.reddy@cdri.res.in. ^[6]

关键词 Amastigotes Benzanilides L. donovani Leishmaniasis Niclosamide Oxyclozanide Salicylanilides

主题词仓鼠亚科(Cricetinae);动物(Animals);水杨酰苯胺类(Salicylanilides);利什曼病, 内脏(Leishmaniasis, Visceral);利什曼病(Leishmaniasis);杜氏利什曼原虫(Leishmania donovani);抗原虫药(Antiprotozoal Agents)

DOI 10.1016/j.ejmech.2022.114996

PMID 36565533

发布时间 2023-01-03

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