A positive feedback circuit between RN7SK snRNA and m<sup>6</sup>A readers is essential for tumorigenesis.

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作者： Xin,Xu ^[1] ; Lifang,Ma ^[2] ; Xiao,Zhang ^[3] ; Susu,Guo ^[2] ; Wanxin,Guo ^[3] ; Yikun,Wang ^[2] ; Shiyu,Qiu ^[1] ; Xiaoting,Tian ^[3] ; Yayou,Miao ^[3] ; Yongchun,Yu ^[3] ; Jiayi,Wang ^[4]

作者单位： Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241, West Huaihai Rd, Shanghai 200030, China; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241, West Huaihai Rd, Shanghai 200030, China. ^[1] Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241, West Huaihai Rd, Shanghai 200030, China. ^[2] Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241, West Huaihai Rd, Shanghai 200030, China. ^[3] Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241, West Huaihai Rd, Shanghai 200030, China; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241, West Huaihai Rd, Shanghai 200030, China; College of Medical Technology, Shanghai Jiao Tong University School of Medicine, No. 197, Ruijin ER Rd, Shanghai 200025, China. Electronic address: Jiayi.wang@sjtu.edu.cn. ^[4]

关键词 RN7SK m(6)A methylation m(6)A readers regulatory mechanism tumorigenesis