Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies.

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第一作者： Veronika,Daniel Lišková

第一单位： Laboratory of Ligand Engineering, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV Research Center, Prumyslova, Vestec, Czechia.

作者： Veronika,Daniel Lišková ^[1] ; Petr,Kosztyu ^[2] ; Milan,Kuchař ^[1] ; Jiří,Černý ^[3] ; Shiv,Bharadwaj ^[1] ; Hana,Petroková ^[1] ; Eliška,Vroblová ^[2] ; Michal,Křupka ^[2] ; Michal,Malý ^[1] ; Tereza,Zosinčuková ^[3] ; Josef,Šulc ^[1] ; Leona,Rašková Kafková ^[1] ; Milan,Raška ^[2] ; Petr,Malý ^[2]

作者单位： Laboratory of Ligand Engineering, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV Research Center, Prumyslova, Vestec, Czechia. ^[1] Department of Immunology, Palacky University Olomouc, Hnevotinska, Olomouc, Czechia. ^[2] Laboratory of Structural Bioinformatics of Proteins, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV Research Center, Prumyslova, Vestec, Czechia. ^[3]

关键词 HIV-1 broadly neutralizing antibody glycoprotein 120 protein engineering protein scaffold vaccine