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SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis.

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作者: Saisai,Guo [1] ; Xiaobo,Lei [2] ; Yan,Chang [3] ; Jianyuan,Zhao [1] ; Jing,Wang [1] ; Xiaojing,Dong [2] ; Qian,Liu [1] ; Zixiong,Zhang [1] ; Lidan,Wang [1] ; Dongrong,Yi [1] ; Ling,Ma [1] ; Quanjie,Li [1] ; Yongxin,Zhang [1] ; Jiwei,Ding [1] ; Chen,Liang [4] ; Xiaoyu,Li [1] ; Fei,Guo [5] ; Jianwei,Wang [6] ; Shan,Cen [7]
作者单位: Department of Immunology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. [1] NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. [2] Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China. [3] Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, QC, Canada. [4] NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. guoafei@ipbcams.ac.cn. [5] NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. wangjw28@163.com. [6] Department of Immunology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. shancen@imb.pumc.edu.cn. [7] CAMS Key Laboratory of Antiviral Drug Research, Chinese Academy of Medical Sciences & Peking Union Medical Sciences, Beijing, China. shancen@imb.pumc.edu.cn. [8]
DOI 10.1038/s41392-022-01239-w
PMID 36575184
发布时间 2023-01-09
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Signal transduction and targeted therapy

Signal transduction and targeted therapy

2022年7卷1期

400页

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