首页> Frontiers in oncology> Case report: Complete pathologic response with first-line immunotherapy combination in a young adult with massive liver dissemination of mismatch repair-deficient metastatic colorectal cancer: Immunological and molecular profiling.

Case report: Complete pathologic response with first-line immunotherapy combination in a young adult with massive liver dissemination of mismatch repair-deficient metastatic colorectal cancer: Immunological and molecular profiling.

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第一作者： Francesca,Bergamo

第一单位： Oncology Unit 1, Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.

作者： Francesca,Bergamo ^[1] ; Silvia,Dalla Santa ^[2] ; Fotios,Loupakis ^[1] ; Krisida,Cerma ^[1] ; Anna,Tosi ^[3] ; Caterina,De Grandis ^[1] ; Anna,Dalla Pietà ^[2] ; Enrico,Gringeri ^[4] ; Valentina,Angerilli ^[5] ; Gaetano,Ramondo ^[6] ; Alessandro,Rago ^[6] ; Fabiola,Cecchi ^[7] ; Stephen,Benz ^[7] ; Umberto,Cillo ^[4] ; Angelo Paolo,Dei Tos ^[5] ; Vittorina,Zagonel ^[1] ; Matteo,Fassan ^[8] ; Antonio,Rosato ^[9] ; Sara,Lonardi ^[10]

作者单位： Oncology Unit 1, Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. ^[1] Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy. ^[2] Immunology and Molecular Oncology Diagnostics Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. ^[3] Hepatobiliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, Padua University Hospital, Padua, Italy. ^[4] Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy. ^[5] Radiology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. ^[6] NantOmics, Rockville, MD, United States. ^[7] Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.;Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. ^[8] Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.;Immunology and Molecular Oncology Diagnostics Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. ^[9] Oncology Unit 3, Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. ^[10]

关键词 MSI-H colorectal cancer complete pathological response ipilimumab nivolumab

DOI 10.3389/fonc.2022.964219

PMID 36578937

发布时间 2023-01-03

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