Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.
第一作者:
Claudia M,Denkinger
第一单位:
Division of Infectious Disease and Tropical Medicine, Department of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany. Claudia.Denkinger@uni-heidelberg.de.;Partner site Heidelberg University Hospital, German Center for Infection Research, Heidelberg, Germany. Claudia.Denkinger@uni-heidelberg.de.
作者:
Claudia M,Denkinger [1]
;
Maike,Janssen [2]
;
Ulrike,Schäkel [2]
;
Julia,Gall [3]
;
Albrecht,Leo [4]
;
Patrick,Stelmach [2]
;
Stefan F,Weber [5]
;
Johannes,Krisam [6]
;
Lukas,Baumann [6]
;
Jacek,Stermann [6]
;
Uta,Merle [7]
;
Markus A,Weigand [8]
;
Christian,Nusshag [9]
;
Lars,Bullinger [10]
;
Jens-Florian,Schrezenmeier [10]
;
Martin,Bornhäuser [11]
;
Nael,Alakel [11]
;
Oliver,Witzke [12]
;
Timo,Wolf [13]
;
Maria J G T,Vehreschild [13]
;
Stefan,Schmiedel [14]
;
Marylyn M,Addo [15]
;
Felix,Herth [16]
;
Michael,Kreuter [17]
;
Phil-Robin,Tepasse [18]
;
Bernd,Hertenstein [19]
;
Mathias,Hänel [20]
;
Anke,Morgner [20]
;
Michael,Kiehl [21]
;
Olaf,Hopfer [21]
;
Mohammad-Amen,Wattad [22]
;
Carl C,Schimanski [23]
;
Cihan,Celik [23]
;
Thorsten,Pohle [24]
;
Matthias,Ruhe [24]
;
Winfried V,Kern [25]
;
Anita,Schmitt [2]
;
Hanns-Martin,Lorenz [2]
;
Margarida,Souto-Carneiro [2]
;
Mary,Gaeddert [5]
;
Niels,Halama [26]
;
Stefan,Meuer [4]
;
Hans-Georg,Kräusslich [27]
;
Barbara,Müller [27]
;
Paul,Schnitzler [27]
;
Sylvia,Parthé [27]
;
Ralf,Bartenschlager [28]
;
Martina,Gronkowski [2]
;
Jennifer,Klemmer [2]
;
Michael,Schmitt [2]
;
Peter,Dreger [2]
;
Katharina,Kriegsmann [2]
;
Richard F,Schlenk [29]
;
Carsten,Müller-Tidow [30]
作者单位:
Division of Infectious Disease and Tropical Medicine, Department of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany. Claudia.Denkinger@uni-heidelberg.de.;Partner site Heidelberg University Hospital, German Center for Infection Research, Heidelberg, Germany. Claudia.Denkinger@uni-heidelberg.de.
[1]
Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.
[2]
NCT Trial Center, National Center for Tumor Diseases, Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany.
[3]
Institute for Clinical Transfusion Medicine and Cell Therapy Heidelberg, Heidelberg, Germany.
[4]
Division of Infectious Disease and Tropical Medicine, Department of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.
[5]
Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany.
[6]
Department of Internal Medicine IV, Heidelberg University Hospital, Heidelberg, Germany.
[7]
Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
[8]
Department of Nephrology, University of Heidelberg, Heidelberg, Germany.
[9]
Department of Hematology, Oncology and Tumor Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
[10]
Department of Internal Medicine I, University Hospital Dresden and Faculty of Medicine Carl Gustav Carus of TU Dresden, Dresden, Germany.
[11]
Department of Infectious Diseases, West German Centre for Infectious Diseases, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
[12]
Department of Internal Medicine, Infectious Diseases, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany.
[13]
Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[14]
Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.;Partner site Hamburg-Lübeck-Borstel-Riems, German Center for Infection Research, Hamburg, Germany.;University Medical Center Hamburg-Eppendorf, Institute for Infection Research and Vaccine Development, Hamburg, Germany.
[15]
Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg and Translational Lung Research Center, Heidelberg, Germany.
[16]
Center for Interstitial and Rare Lung Diseases, Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg and German Center for Lung Research, Heidelberg, Germany.
[17]
Department of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, Münster, Germany.
[18]
Medical Department I, Klinikum Bremen-Mitte, Bremen, Germany.
[19]
Department of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany.
[20]
Department of Internal Medicine I, Frankfurt (Oder) General Hospital, Frankfurt (Oder), Germany.
[21]
Department of Hematology, Oncology, Palliative Care and Stem Cell Transplantation, Klinikum Hochsauerland, Meschede, Germany.
[22]
Department of Internal Medicine II, Klinikum Darmstadt, Darmstadt, Germany.
[23]
Department of Internal Medicine I, Klinikum Herford, Herford, Germany.
[24]
Department of Medicine II, Division of Infectious Diseases and Travel Medicine, University Medical Centre Freiburg, Freiburg, Germany.
[25]
Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.;Department of Translational Immunotherapy (D240), German Cancer Research Center, Heidelberg, Germany.;Helmholtz Institute for Translational Oncology, Mainz, Germany.
[26]
Department of Infectious Diseases, Virology, Heidelberg University Hospital, Heidelberg, Germany.
[27]
Department of Infectious Diseases, Molecular Virology, Heidelberg University Hospital, Heidelberg, Germany.
[28]
Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.;NCT Trial Center, National Center for Tumor Diseases, Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany.;Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.
[29]
Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany. carsten.mueller-tidow@med.uni-heidelberg.de.;National Center for Tumor Diseases, Heidelberg, Germany. carsten.mueller-tidow@med.uni-heidelberg.de.
[30]
主题词
人类(Humans);免疫法, 被动(Immunization, Passive);治疗结果(Treatment Outcome);抗体, 病毒(Antibodies, Viral);肿瘤(Neoplasms)
DOI
10.1038/s43018-022-00503-w
PMID
36581734
发布时间
2024-09-11
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Nature cancer
Nature cancer
2023年4卷1期
96-107页
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