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Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice.

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作者单位: Department of Pathophysiology, Institute for Translational Medicine, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: janos.garai@gmail.com. [1] Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: balazs.radnai@aok.pte.hu. [2] Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: eszter.vamos@aok.pte.hu. [3] Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: dominika.kovacs@aok.pte.hu. [4] Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: viola.vantus@aok.pte.hu. [5] Department of Thermophysiology, Institute for Translational Medicine, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: zoltan.rumbus@aok.pte.hu. [6] Department of Thermophysiology, Institute for Translational Medicine, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: eszter.pakai@aok.pte.hu. [7] Department of Thermophysiology, Institute for Translational Medicine, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: andras.garami@aok.pte.hu. [8] Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: gergely.gulyas@aok.pte.hu. [9] Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: attila.agocs@aok.pte.hu. [10] Department of Pharmaceutical Chemistry, Semmelweis University, 9 Hőgyes E. str., Budapest, H-1092, Hungary. Electronic address: kreko.marcell@pharma.semmelweis-univ.hu. [11] Department of Pharmacology and Neuroscience, The University of North Texas Health Science Centre, Fort Worth, TX, USA. Electronic address: khadiza.zaman@unthsc.edu. [12] Department of Pharmacology and Neuroscience, The University of North Texas Health Science Centre, Fort Worth, TX, USA. Electronic address: laszlo.prokai@unthsc.edu. [13] Department of Pharmaceutical Chemistry, Semmelweis University, 9 Hőgyes E. str., Budapest, H-1092, Hungary. Electronic address: orfi.laszlo@pharma.semmelweis-univ.hu. [14] Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: peter.jakus@aok.pte.hu. [15] Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, 12 Szigeti str., Pécs, H-7624, Hungary. Electronic address: lorand.tamas@gmail.com. [16]
DOI 10.1016/j.ejmech.2022.115050
PMID 36587420
发布时间 2023-01-17
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