Extracellular vesicle-derived CircWhsc1 promotes cardiomyocyte proliferation and heart repair by activating TRIM59/STAT3/Cyclin B2 pathway.

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作者： Guoquan,Wei ^[1] ; Chuling,Li ^[1] ; Xiaoqian,Jia ^[1] ; Jingfang,Xie ^[1] ; Zhenquan,Tang ^[1] ; Ming,Jin ^[1] ; Qiqi,Chen ^[1] ; Yili,Sun ^[1] ; Sisi,He ^[1] ; Xinzhong,Li ^[1] ; Yanmei,Chen ^[1] ; Hao,Zheng ^[1] ; Wangjun,Liao ^[2] ; Yulin,Liao ^[1] ; Jianping,Bin ^[3] ; Senlin,Huang ^[4]

作者单位： Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, 510515 Guangzhou, China. ^[1] Department of Oncology, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, China. ^[2] Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, 510515 Guangzhou, China. Electronic address: jianpingbin@hotmail.com. ^[3] Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, China; Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, 510515 Guangzhou, China. Electronic address: huangsenlin11@126.com. ^[4]

关键词 Cardiac regeneration CircRNA Endothelial cell Extracellular vesicle

主题词动物(Animals);小鼠(Mice);细胞增殖(Cell Proliferation);细胞周期蛋白B2(Cyclin B2);心肌梗死(Myocardial Infarction);肌细胞, 心脏(Myocytes, Cardiac);RNA(RNA)

DOI 10.1016/j.jare.2022.12.014

PMID 36587763

发布时间 2023-11-23

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Journal of advanced research

2023年53卷

199-218页

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Extracellular vesicle-derived CircWhsc1 promotes cardiomyocyte proliferation and heart repair by activating TRIM59/STAT3/Cyclin B2 pathway.

Journal of advanced research

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Journal of advanced research

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Extracellular vesicle-derived CircWhsc1 promotes cardiomyocyte proliferation and heart repair by activating TRIM59/STAT3/Cyclin B2 pathway.

Journal of advanced research

相似文献

Journal of advanced research

相关期刊

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