Methods to identify protein targets of metal-based drugs.

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第一作者： Lukas,Skos

第一单位： Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria; Doctoral School of Chemistry, University of Vienna, 1090 Vienna, Austria.

作者： Lukas,Skos ^[1] ; Yasmin,Borutzki ^[2] ; Christopher,Gerner ^[3] ; Samuel M,Meier-Menches ^[4]

作者单位： Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria; Doctoral School of Chemistry, University of Vienna, 1090 Vienna, Austria. ^[1] Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria; Doctoral School of Chemistry, University of Vienna, 1090 Vienna, Austria; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria. ^[2] Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria; Joint Metabolome Facility, University of Vienna and Medical University Vienna, 1090 Vienna, Austria. ^[3] Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria; Joint Metabolome Facility, University of Vienna and Medical University Vienna, 1090 Vienna, Austria. Electronic address: samuel.meier-menches@univie.ac.at. ^[4]

关键词 Chemoproteomics Drug discovery Inorganic drug discovery Metallodrug Omics Probes Target identification

主题词抗肿瘤药(Antineoplastic Agents);铂(Platinum);钌(Ruthenium);金(Gold);DNA(DNA);配位络合物(Coordination Complexes)

DOI 10.1016/j.cbpa.2022.102257

PMID 36599256

发布时间 2023-03-23

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