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Virtual Screening, Synthesis, and Biological Evaluation of Some Carbohydrazide Derivatives as Potential DPP-IV Inhibitors.

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第一作者： Prerana B,Jadhav

第一单位： S.N.D. College of Pharmacy, Babhulgaon, Yeola 423401, India.

作者： Prerana B,Jadhav ^[1] ; Shailaja B,Jadhav ^[2] ; Mehrukh,Zehravi ^[3] ; Mohammad S,Mubarak ^[4] ; Fahadul,Islam ^[5] ; Philippe,Jeandet ^[6] ; Sharuk L,Khan ^[7] ; Nazmul,Hossain ^[5] ; Salma,Rashid ^[5] ; Long Chiau,Ming ^[8] ; Md Moklesur Rahman,Sarker ^[9] ; Mohd Fahami Nur,Azlina ^[10]

作者单位： S.N.D. College of Pharmacy, Babhulgaon, Yeola 423401, India. ^[1] PES's Modern College of Pharmacy, Nigdi, Pune 411044, India. ^[2] Department of Clinical Pharmacy Girls Section, Prince Sattam Bin Abdul Aziz University Alkharj, Al-Kharj 11942, Saudi Arabia. ^[3] Department of Chemistry, The University of Jordan, Amman 11942, Jordan. ^[4] Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh. ^[5] Research Unit-Induced Resistance and Plant Bioprotection, University of Reims, EA 4707-USC INRAe 1488, SFR Condorcet FR CNRS 3417, 51687 Reims, France. ^[6] Department of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa 413520, India. ^[7] School of Medical and Life Sciences, Sunway University, Bandar Sunway 47500, Malaysia. ^[8] Department of Pharmacy, State University of Bangladesh, 77 Satmasjid Road, Dhanmondi, Dhaka 1205, Bangladesh.;Health Med Science Research Network, 3/1, Block F, Lalmatia, Dhaka 1207, Bangladesh. ^[9] Department of Pharmacology, Faculty of Medicine, University Kebangsaan Malaysia, Jalan Yacob Latif, Kuala Lumpur 56000, Malaysia. ^[10]

关键词 2P8S ADMET DPP-IV carbohydrazide in vivo molecular docking

医学主题词动物(Animals);二肽基肽酶Ⅳ抑制剂(Dipeptidyl-Peptidase IV Inhibitors);糖尿病, 2型(Diabetes Mellitus, Type 2);血糖(Blood Glucose);降血糖药(Hypoglycemic Agents);二肽基肽酶4(Dipeptidyl Peptidase 4)

DOI 10.3390/molecules28010149

PMID 36615348

发布时间 2023-01-11

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