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How many brain metastases can be treated with stereotactic radiosurgery before the radiation dose delivered to normal brain tissue rivals that associated with standard whole brain radiotherapy?

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第一作者： Stewart J,Becker

第一单位： Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

作者： Stewart J,Becker ^[1] ; Evan J,Lipson ^[2] ; Gabor,Jozsef ^[3] ; Jason K,Molitoris ^[1] ; Joshua S,Silverman ^[4] ; Joseph,Presser ^[5] ; Douglas,Kondziolka ^[6]

作者单位： Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA. ^[1] Bloomberg∼Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA. ^[2] Department of Radiation Oncology, Weill Cornell Medicine, New York, New York, USA. ^[3] Department of Radiation Oncology, New York University Langone Medical Center, New York, New York, USA. ^[4] Department of Radiation Oncology, Mount Sinai South Nassau, Oceanside, New York, USA. ^[5] Department of Radiation Oncology, New York University Langone Medical Center, New York, New York, USA.;Department of Neurosurgery, New York University Langone Medical Center, New York, New York, USA. ^[6]

关键词 brain metastases gamma knife radiation toxicity stereotactic radiosurgery whole brain radiotherapy