Fibrosis resolution in the mouse liver: Role of Mmp12 and potential role of calpain 1/2.

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作者： Toshifumi,Sato ^[1] ; Kimberly Z,Head ^[2] ; Jiang,Li ^[1] ; Christine E,Dolin ^[3] ; Daniel,Wilkey ^[4] ; Nolan,Skirtich ^[5] ; Katelyn,Smith ^[6] ; Dylan D,McCreary ^[7] ; Sylvia,Liu ^[6] ; Juliane I,Beier ^[7] ; Aatur D,Singhi ^[8] ; Ryan M,McEnaney ^[1] ; Michael L,Merchant ^[8] ; Gavin E,Arteel ^[9]

作者单位： Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, United States. ^[1] Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213, United States. ^[2] Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40292, United States. ^[3] Department of Medicine, Division of Nephrology and Hypertension, University of Louisville, Louisville, KY 40292, United States. ^[4] University of Louisville Alcohol Research Center, University of Louisville, Louisville, KY 40292, United States. ^[5] Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, United States. ^[6] Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, United States. ^[7] Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA 15213, United States. ^[8] Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA 15213, United States. ^[9]

关键词 CCl4, carbon tetrachloride ECM, extracellular matrix ELISA, enzyme-linked immunosorbent assay Elastin Fibrosis GO, gene ontology LC-MS/MS, liquid Chromatography with tandem mass spectrometry MMP, matrix metalloprotease MMP-12 MPM, multiphoton microscopy SDS, sodium dodecyl sulfate rtPCR, reverse-transcriptase polymerase chain reaction

DOI 10.1016/j.mbplus.2022.100127

PMID 36632559

发布时间 2024-03-09

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Matrix biology plus

2023年17卷

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Fibrosis resolution in the mouse liver: Role of Mmp12 and potential role of calpain 1/2.

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Fibrosis resolution in the mouse liver: Role of Mmp12 and potential role of calpain 1/2.

Matrix biology plus

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