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ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy.

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第一作者： Dong-Oh,Seo

第一单位： Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.

作者： Dong-Oh,Seo ^[1] ; David,O'Donnell ^[2] ; Nimansha,Jain ^[1] ; Jason D,Ulrich ^[1] ; Jasmin,Herz ^[3] ; Yuhao,Li ^[4] ; Mackenzie,Lemieux ^[3] ; Jiye,Cheng ^[2] ; Hao,Hu ^[1] ; Javier R,Serrano ^[1] ; Xin,Bao ^[1] ; Emily,Franke ^[1] ; Maria,Karlsson ^[2] ; Martin,Meier ^[2] ; Su,Deng ^[2] ; Chandani,Desai ^[2] ; Hemraj,Dodiya ^[5] ; Janaki,Lelwala-Guruge ^[2] ; Scott A,Handley ^[6] ; Jonathan,Kipnis ^[3] ; Sangram S,Sisodia ^[5] ; Jeffrey I,Gordon ^[7] ; David M,Holtzman ^[8]

作者单位： Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. ^[1] The Edison Family Center for Genome Sciences and Systems Biology and the Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO, USA. ^[2] Center for Brain Immunology and Glia (BIG), Washington University School of Medicine, St. Louis, MO, USA.;Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. ^[3] Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. ^[4] Department of Neurobiology, The University of Chicago, Chicago, IL, USA. ^[5] Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. ^[6] The Edison Family Center for Genome Sciences and Systems Biology and the Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO, USA.;Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. ^[7] Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.;Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. ^[8]