首页> The Journal of biological chemistry> Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation.

Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation.

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第一作者： Guido,Barbieri

第一单位： Department of Biology, Faculty of Natural Sciences and Technology, Saarland University, Saarbruecken, Germany.

作者： Guido,Barbieri ^[1] ; Julien,Simon ^[1] ; Cristina R,Lupusella ^[1] ; Fabio,Pereira ^[1] ; Francesco,Elia ^[1] ; Hadar,Meyer ^[2] ; Maya,Schuldiner ^[2] ; Steven D,Hanes ^[3] ; Duy,Nguyen ^[4] ; Volkhard,Helms ^[4] ; Karin,Römisch ^[5]

作者单位： Department of Biology, Faculty of Natural Sciences and Technology, Saarland University, Saarbruecken, Germany. ^[1] Department of Molecular Genetics, Weizmann Institute of Sciences, Rehovot, Israel. ^[2] Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York, USA. ^[3] Center for Bioinformatics, Faculty of Natural Sciences and Technology, Saarland University, Saarbruecken, Germany. ^[4] Department of Biology, Faculty of Natural Sciences and Technology, Saarland University, Saarbruecken, Germany. Electronic address: k.roemisch@mx.uni-saarland.de. ^[5]

关键词 Ess1/PIN1 Sec61 channel endoplasmic reticulum (ER)protein isomerase protein phosphorylation protein secretion protein translocation