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首页> Lipids in health and disease> Curcumin suppresses cell proliferation and reduces cholesterol absorption in Caco-2 cells by activating the TRPA1 channel.

Curcumin suppresses cell proliferation and reduces cholesterol absorption in Caco-2 cells by activating the TRPA1 channel.

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作者： Si,Qin ^[1] ; Qian,Su ^[1] ; Xiang,Li ^[2] ; Muqing,Shao ^[1] ; Yindi,Zhang ^[1] ; Fadong,Yu ^[1] ; Yinxing,Ni ^[3] ; Jian,Zhong ^[4]

作者单位： Department of Endocrinology, The Third Affiliated Hospital of Chongqing Medical University, No.1, Shuanghu Branch Road, Chongqing, 401120, China. ^[1] College of Chemistry and Molecular Engineering, Peking University, 100871, Beijing, China. ^[2] Department of Endocrinology, The Third Affiliated Hospital of Chongqing Medical University, No.1, Shuanghu Branch Road, Chongqing, 401120, China. 650272@hospital.cqmu.edu.cn. ^[3] Department of Endocrinology, The Third Affiliated Hospital of Chongqing Medical University, No.1, Shuanghu Branch Road, Chongqing, 401120, China. 651170@cqmu.edu.cn. ^[4]

关键词 Caco-2 cells Cholesterol absorption Curcumin NPC1L1 Proliferation TRPA1

主题词人类(Humans);膜转运蛋白质类(Membrane Transport Proteins);膜蛋白质类(Membrane Proteins);Caco-2细胞(Caco-2 Cells);姜黄素(Curcumin);PPARγ(PPAR gamma);胆固醇调节元件结合蛋白质1(Sterol Regulatory Element Binding Protein 1);钙(Calcium);胆固醇(Cholesterol);细胞增殖(Cell Proliferation);肠吸收(Intestinal Absorption)

DOI 10.1186/s12944-022-01750-7

PMID 36641489

发布时间 2023-01-17

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Lipids in health and disease

Lipids in health and disease

2023年22卷1期

6页

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