Sequestration of Gβγ by deubiquitinated arrestins into the nucleus as a novel desensitization mechanism of G protein-coupled receptors.

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作者： Xiao,Min ^[1] ; Ningning,Sun ^[1] ; Shujie,Wang ^[1] ; Xiaohan,Zhang ^[1] ; Kyeong-Man,Kim ^[2]

作者单位： Department of Pharmacology, College of Pharmacy, Chonnam National University, Gwangju, 61186, Republic of Korea. ^[1] College of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, Guizhou, China. ^[2] Department of Pharmacology, College of Pharmacy, Chonnam National University, Gwangju, 61186, Republic of Korea. kmkim@jnu.ac.kr. ^[3]

关键词 Desensitization Dopamine D2-like receptor Nuclear trafficking Src USP33 β2 adrenoceptor

主题词抑制蛋白类(Arrestins);抑制蛋白(Arrestin);信号传导(Signal Transduction);磷酰化(Phosphorylation);受体, G-蛋白偶联(Receptors, G-Protein-Coupled)

DOI 10.1186/s12964-022-01013-z

PMID 36658650

发布时间 2023-02-01

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准确一般字义偏差语意偏离译文作用小提交