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Enhancement of the haemostatic effect of platelets in the presence of high normal concentrations of von Willebrand factor for critically ill patients needing platelet transfusion-a protocol for the will-plate randomised controlled trial.

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第一作者： Goetz,Herrmann

第一单位： Department for Anesthesia, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland.

作者： Goetz,Herrmann ^[1] ; Andrea,Blum ^[2] ; Daniel,Bolliger ^[3] ; Rita,Achermann ^[2] ; Anna,Estermann ^[2] ; Caroline Eva,Gebhard ^[2] ; Anne,Henn ^[4] ; Jan,Huber ^[2] ; Jasprit,Singh ^[2] ; Atanas,Todorov ^[5] ; Tatjana,Zehnder ^[2] ; Núria,Zellweger ^[2] ; Andreas,Buser ^[6] ; Dimitrios A,Tsakiris ^[7] ; Alexa,Hollinger ^[8] ; Martin,Siegemund ^[9]

作者单位： Department for Anesthesia, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland. ^[1] Intensive Care Unit, University Hospital Basel, Spitalstrasse 21, CH-4031, Basel, Switzerland. ^[2] Department for Anesthesia, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland.;Medical Faculty of the University of Basel, Klingelbergstrasse 61, 4056, Basel, Switzerland. ^[3] Hospital Pharmacy, University Hospital Basel, Spitalstrasse 26, 4031, Basel, Switzerland. ^[4] Department of Nuclear Medicine, Cardiovascular Gender Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. ^[5] Medical Faculty of the University of Basel, Klingelbergstrasse 61, 4056, Basel, Switzerland.;Transfusion Medicine and Regional Blood Transfusion Service Swiss Red Cross, Department of Hematology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland. ^[6] Medical Faculty of the University of Basel, Klingelbergstrasse 61, 4056, Basel, Switzerland.;Department for Diagnostic Haematology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland. ^[7] Intensive Care Unit, University Hospital Basel, Spitalstrasse 21, CH-4031, Basel, Switzerland. alexa.hollinger@usb.ch.;Medical Faculty of the University of Basel, Klingelbergstrasse 61, 4056, Basel, Switzerland. alexa.hollinger@usb.ch. ^[8] Intensive Care Unit, University Hospital Basel, Spitalstrasse 21, CH-4031, Basel, Switzerland.;Medical Faculty of the University of Basel, Klingelbergstrasse 61, 4056, Basel, Switzerland. ^[9]

关键词 Adult intensive and critical care Blood loss Randomised controlled trial VerifyNow von Willebrand factor