Fighting Antibiotic Resistance: New Pyrimidine-Clubbed Benzimidazole Derivatives as Potential DHFR Inhibitors.

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第一作者： M Akiful,Haque

第一单位： Department of Pharmaceutical Analysis, School of Pharmacy, Anurag University, Ghatkesar, Hyderabad 500088, India.

作者： M Akiful,Haque ^[1] ; Akash,Marathakam ^[2] ; Ritesh,Rana ^[3] ; Samar J,Almehmadi ^[4] ; Vishal B,Tambe ^[5] ; Manoj S,Charde ^[6] ; Fahadul,Islam ^[7] ; Falak A,Siddiqui ^[8] ; Giulia,Culletta ^[9] ; Anna Maria,Almerico ^[9] ; Marco,Tutone ^[9] ; Sharuk L,Khan ^[8]

作者单位： Department of Pharmaceutical Analysis, School of Pharmacy, Anurag University, Ghatkesar, Hyderabad 500088, India. ^[1] National College of Pharmacy, Kozhikode 673602, India. ^[2] Department of Pharmaceutics, Himachal Institute of Pharmaceutical Education and Research (HIPER), Bela, Nadaun, Hamirpur 177042, India. ^[3] Department of Chemistry, Faculty of Applied Science, Umm-Al-Qura University, Makkah 24382, Saudi Arabia. ^[4] Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni 413736, India. ^[5] Department of Pharmaceutical Chemistry, Government College of Pharmacy, Karad 415124, India. ^[6] Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh. ^[7] Department of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa 413520, India. ^[8] Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università degli Studi di Palermo, 90123 Palermo, Italy. ^[9]

关键词 ADMETlab 2.0 DHFR antibacterial antifungal benzimidazoles molecular docking pyrimidines