Jietacin Derivative Inhibits TNF-α-Mediated Inflammatory Cytokines Production via Suppression of the NF-κB Pathway in Synovial Cells.

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作者： Kyoko,Muneshige ^[1] ; Yuki,Inahashi ^[2] ; Makoto,Itakura ^[3] ; Masato,Iwatsuki ^[4] ; Tomoyasu,Hirose ^[2] ; Gen,Inoue ^[3] ; Masashi,Takaso ^[2] ; Toshiaki,Sunazuka ^[3] ; Yoshihisa,Ohashi ^[1] ; Etsuro,Ohta ^[1] ; Kentaro,Uchida ^[2]

作者单位： Department of Orthopedic Surgery, Kitasato University School of Medicine, 1-15-1 Minami-ku, Kitasato, Sagamihara City 252-0374, Japan. ^[1] Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Minato-ku, Shirokane, Tokyo 108-8641, Japan. ^[2] Ōmura Satoshi Memorial Institute, Kitasato University, 5-9-1 Minato-ku, Shirokane, Tokyo 108-8641, Japan. ^[3] Department of Biochemistry, Kitasato University School of Medicine, 1-15-1 Minami-ku, Kitasato, Sagamihara City 252-0374, Japan. ^[4] Department of Immunology II, Kitasato University School of Allied Health Sciences, 1-15-1 Minami-ku, Kitasato, Sagamihara City 252-0375, Japan. ^[5] Shonan University of Medical Sciences Research Institute, Nishikubo 500, Chigasaki 253-0083, Japan. ^[6]

关键词 NF-κB jietacin derivative osteoarthritis synovial inflammation

DOI 10.3390/ph16010005

PMID 36678502

发布时间 2023-03-08

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准确一般字义偏差语意偏离译文作用小提交