Inhalable Polymeric Nanoparticles for Pulmonary Delivery of Antimicrobial Peptide SET-M33: Antibacterial Activity and Toxicity In Vitro and In Vivo.

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第一作者： Laura,Cresti

第一单位： Laboratory of Clinical Pathology, Santa Maria alle Scotte University Hospital, 53100 Siena, Italy.

作者： Laura,Cresti ^[1] ; Gemma,Conte ^[2] ; Giovanni,Cappello ^[3] ; Jlenia,Brunetti ^[4] ; Chiara,Falciani ^[2] ; Luisa,Bracci ^[3] ; Fabiana,Quaglia ^[3] ; Francesca,Ungaro ^[3] ; Ivana,d'Angelo ^[1] ; Alessandro,Pini ^[3]

作者单位： Laboratory of Clinical Pathology, Santa Maria alle Scotte University Hospital, 53100 Siena, Italy. ^[1] SetLance srl, 53100 Siena, Italy. ^[2] Department of Medical Biotechnology, University of Siena, 53100 Siena, Italy. ^[3] Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", 81100 Caserta, Italy. ^[4] Department of Pharmacy, University of Naples Federico II, 80131 Napoli, Italy. ^[5]

关键词 Pseudomonas aeruginosa aerosolization antimicrobial peptides antimicrobial resistance inhalable formulations lung delivery nanoparticle properties nanoparticle/mucus interactions polymeric nanoparticles

DOI 10.3390/pharmaceutics15010003

PMID 36678633

发布时间 2023-02-01

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