Stable High-Concentration Monoclonal Antibody Formulations Enabled by an Amphiphilic Copolymer Excipient.

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作者： John H,Klich ^[1] ; Catherine M,Kasse ^[2] ; Joseph L,Mann ^[2] ; Yaoqi,Huang ^[3] ; Andrea I,d'Aquino ^[2] ; Abigail K,Grosskopf ^[3] ; Julie,Baillet ^[2] ; Gerald G,Fuller ^[3] ; Eric A,Appel ^[4]

作者单位： Department of Bioengineering, Stanford University, Stanford, CA 94305, USA. ^[1] Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA. ^[2] Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA. ^[3] Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA; Department of Pediatrics - Endocrinology, Stanford University School of Medicine, Stanford, CA 94305, USA; ChEM-H Institute, Stanford University, Stanford, CA 94305, USA; Woods Institute for the Environment, Stanford University, Stanford, CA 94305, USA. ^[4]

关键词 Antibodies Biopharmaceutical Drug Delivery Excipient Formulation

DOI 10.1002/adtp.202200102

PMID 36684707

发布时间 2023-07-03

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Advanced therapeutics

2023年6卷1期

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Stable High-Concentration Monoclonal Antibody Formulations Enabled by an Amphiphilic Copolymer Excipient.

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Stable High-Concentration Monoclonal Antibody Formulations Enabled by an Amphiphilic Copolymer Excipient.

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