Exercise Improves Cerebral Blood Flow and Functional Outcomes in an Experimental Mouse Model of Vascular Cognitive Impairment and Dementia (VCID).

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作者： Mohammad Badruzzaman,Khan ^[1] ; Haroon,Alam ^[2] ; Shahneela,Siddiqui ^[2] ; Muhammad Fasih,Shaikh ^[2] ; Abhinav,Sharma ^[2] ; Amna,Rehman ^[2] ; Babak,Baban ^[3] ; Ali S,Arbab ^[4] ; David C,Hess ^[2]

作者单位： Department of Neurology, Medical College of Georgia, Augusta University, 1120 15thStreet, CA 1053, Augusta, GA, 30912, USA. mkhan@augusta.edu. ^[1] Department of Neurology, Medical College of Georgia, Augusta University, 1120 15thStreet, CA 1053, Augusta, GA, 30912, USA. ^[2] Department of Oral Biology, Dental College of Georgia, Augusta University, Augusta, GA, 30912, USA. ^[3] Georgia Cancer Center, Augusta University, Augusta, GA, 30912, USA. ^[4]

关键词 AMPK Chronic cerebral hypoperfusion Exercise (EXR), Cerebral blood flow (CBF)Neurobehavioral test Phospho-AMPK RBC deformability, White matter (WM) degeneration, Nitric oxide synthase (NOS3)Vascular cognitive impairment and dementia (VCID)p-NOS3

主题词动物(Animals);小鼠(Mice);AMP活化蛋白激酶类(AMP-Activated Protein Kinases);脑缺血(Brain Ischemia);脑血管循环(Cerebrovascular Circulation);痴呆, 血管性(Dementia, Vascular);疾病模型, 动物(Disease Models, Animal)

DOI 10.1007/s12975-023-01124-w

PMID 36689081

发布时间 2024-03-20

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