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Low-dose intravenous and subcutaneous CIS43LS monoclonal antibody for protection against malaria (VRC 612 Part C): a phase 1, adaptive trial.

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第一作者： Kirsten E,Lyke

第一单位： Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: klyke@som.umaryland.edu.

作者： Kirsten E,Lyke ^[1] ; Andrea A,Berry ^[2] ; Kaitlin,Mason ^[2] ; Azza H,Idris ^[3] ; Mark,O'Callahan ^[3] ; Myra,Happe ^[3] ; Larisa,Strom ^[3] ; Nina M,Berkowitz ^[3] ; Mercy,Guech ^[3] ; Zonghui,Hu ^[4] ; Mike,Castro ^[3] ; Manjula,Basappa ^[3] ; Lu,Wang ^[3] ; Kwang,Low ^[3] ; LaSonji A,Holman ^[3] ; Floreliz,Mendoza ^[3] ; Ingelise J,Gordon ^[3] ; Sarah H,Plummer ^[3] ; Olga,Trofymenko ^[3] ; Kathleen S,Strauss ^[2] ; Sudhaunshu,Joshi ^[2] ; Biraj,Shrestha ^[2] ; Matthew,Adams ^[2] ; Andrezza Campos,Chagas ^[5] ; Jittawadee R,Murphy ^[5] ; Judy,Stein ^[3] ; Somia,Hickman ^[3] ; Andrew,McDougal ^[3] ; Bob,Lin ^[3] ; Sandeep R,Narpala ^[3] ; Sandra,Vazquez ^[3] ; Leonid,Serebryannyy ^[3] ; Adrian,McDermott ^[3] ; Martin R,Gaudinski ^[6] ; Edmund V,Capparelli ^[7] ; Emily E,Coates ^[3] ; Richard L,Wu ^[6] ; Julie E,Ledgerwood ^[3] ; Lesia K,Dropulic ^[3] ; Robert A,Seder ^[3] ; VRC 612 Part C Study Team

作者单位： Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: klyke@som.umaryland.edu. ^[1] Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA. ^[2] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. ^[3] Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. ^[4] Entomology Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA. ^[5] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA; United States Public Health Service Commissioned Corps, Rockville, MD, USA. ^[6] School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA. ^[7]