<i>Toxoplasma</i> IWS1 Determines Fitness in Interferon-γ-Activated Host Cells and Mice by Indirectly Regulating ROP18 mRNA Expression.

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作者： Emi,Hashizaki ^[1] ; Miwa,Sasai ^[1] ; Daisuke,Okuzaki ^[2] ; Tsubasa,Nishi ^[3] ; Takashi,Kobayashi ^[4] ; Shiroh,Iwanaga ^[5] ; Masahiro,Yamamoto ^[6]

作者单位： Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan. ^[1] Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan. ^[2] Department of Immunoparasitology, Center for Infectious Disease Education and Research, Osaka University, Suita, Osaka, Japan. ^[3] Genome Information Research Center, Osaka University, Suita, Osaka, Japan. ^[4] Department of Medical Zoology, Faculty of Medicine, Mie University, Mie, Japan. ^[5] Infectious Disease Control, Faculty of Medicine, Research Center for Global and Local Infectious Diseases, Oita University, Oita, Japan. ^[6] Department of Molecular Parasitology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan. ^[7]

关键词 IFN-γ IWS1 ROP18 Toxoplasma interferons parasitophorous vacuole transcriptional regulation virulence virulence factors