B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors.

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第一作者： Daniel F,Kaemena

第一单位： Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK.

作者： Daniel F,Kaemena ^[1] ; Masahito,Yoshihara ^[2] ; Meryam,Beniazza ^[3] ; James,Ashmore ^[4] ; Suling,Zhao ^[1] ; Mårten,Bertenstam ^[1] ; Victor,Olariu ^[1] ; Shintaro,Katayama ^[5] ; Keisuke,Okita ^[5] ; Simon R,Tomlinson ^[2] ; Kosuke,Yusa ^[6] ; Keisuke,Kaji ^[7]

作者单位： Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK. ^[1] Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden. ^[2] Institute for Advanced Academic Research, Chiba University, Chiba, Japan. ^[3] Department of Artificial Intelligence Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan. ^[4] Computational Biology and Biological Physics, Lund University, Lund, Sweden. ^[5] Research Programs Unit, Stem Cells and Metabolism Research Program (STEMM), University of Helsinki, Helsinki, Finland. ^[6] Folkhälsan Research Center, Helsinki, Finland. ^[7] Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan. ^[8] Stem Cell Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK. ^[9] Stem Cell Genetics, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan. ^[10] Centre for Regenerative Medicine, Institute for Regenaration and Repair, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh, Scotland, UK. keisuke.kaji@ed.ac.uk. ^[11]

主题词动物(Animals);小鼠(Mice);染色质(Chromatin);诱导多能干细胞(Induced Pluripotent Stem Cells);锌指(Zinc Fingers)

DOI 10.1038/s41467-023-36097-9

PMID 36717582

发布时间 2023-03-15

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