Oral delivery of bi-autoantigens by bacterium-like particles (BLPs) against autoimmune diabetes in NOD mice.

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作者： Ruifeng,Mao ^[1] ; Jin,Wang ^[2] ; Ying,Xu ^[1] ; Yuqi,Wang ^[1] ; Mengmeng,Wu ^[1] ; Lixia,Mao ^[1] ; Yingying,Chen ^[1] ; Dengchao,Li ^[1] ; Tong,Zhang ^[1] ; Enjie,Diao ^[1] ; Zhenjing,Chi ^[3] ; Yefu,Wang ^[4] ; Xin,Chang ^[2]

作者单位： Jiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection, School of Life Sciences, Huaiyin Normal University, Huai'an223300, China. ^[1] Nanjing Lishui People's Hospital, Zhongda Hospital Lishui Branch, Southeast University, Nanjing211200, China. ^[2] Huai'an First People's Hospital, Nanjing Medical University, Huai'an223300, China. ^[3] State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan430072, China. ^[4]

关键词 Type 1 diabetes mellitus autoantigen bacterium-like particles immune tolerance oral vaccination

主题词动物(Animals);小鼠(Mice);糖尿病, 1型(Diabetes Mellitus, Type 1);小鼠, 近交NOD(Mice, Inbred NOD);自身抗原(Autoantigens);疫苗(Vaccines);疫苗, 联合(Vaccines, Combined)

DOI 10.1080/10717544.2023.2173339

PMID 36719009

发布时间 2023-02-03

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