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Self-Administration of Burosumab in Children and Adults with X-Linked Hypophosphataemia in Two Open-Label, Single-Arm Clinical Studies.

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第一作者： Takuo,Kubota

第一单位： Department of Paediatrics, Osaka University Graduate School of Medicine, Osaka, Japan.

作者： Takuo,Kubota ^[1] ; Noriyuki,Namba ^[2] ; Hiroyuki,Tanaka ^[3] ; Koji,Muroya ^[4] ; Yasuo,Imanishi ^[5] ; Yasuhiro,Takeuchi ^[6] ; Masanori,Kanematsu ^[7] ; Wei,Sun ^[8] ; Yoshiki,Seino ^[9] ; Keiichi,Ozono ^[1]

作者单位： Department of Paediatrics, Osaka University Graduate School of Medicine, Osaka, Japan. ^[1] Division of Paediatrics and Perinatology, Tottori University Faculty of Medicine, Tottori, Japan. ^[2] Department of Paediatrics, Okayama Saiseikai General Hospital, Okayama, Japan. ^[3] Department of Endocrinology and Metabolism, Kanagawa Children's Medical Centre, Kanagawa, Japan. ^[4] Department of Metabolism, Endocrinology and Molecular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan. ^[5] Endocrine Centre, Toranomon Hospital, Tokyo, Japan.;Okinaka Memorial Institute for Medical Research, Tokyo, Japan. ^[6] Kyowa Kirin Co., Ltd., Oteomachi Financial City Grand Cube, 1-9-2 Otemachi, Chiyoda-ku, Tokyo, Japan. masanori.kanematsu.vn@kyowakirin.com. ^[7] Kyowa Kirin, Inc., 212 Carnegie Centre, Princeton, NJ, 08540, USA. ^[8] Department of Paediatrics, Osaka Hospital, Japan Community Healthcare Organisation, Osaka, Japan. ^[9]

关键词 Anti-FGF23 antibody Burosumab Fibroblast growth factor 23 Self-administration Serum phosphate Subcutaneous injection X-linked hypophosphataemia

医学主题词人类(Humans);成年人(Adult);儿童(Child);抗体, 单克隆(Antibodies, Monoclonal);磷酸盐类(Phosphates)

DOI 10.1007/s12325-022-02412-x

PMID 36719566

发布时间 2023-10-03

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准确一般字义偏差语意偏离译文作用小提交