首页> Pharmacological reports : PR> L-proline transporter inhibitor (LQFM215) promotes neuroprotection in ischemic stroke.

L-proline transporter inhibitor (LQFM215) promotes neuroprotection in ischemic stroke.

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第一作者： Gustavo Almeida,Carvalho

第一单位： Department of Pharmacology, Federal University of Goias, Goiânia, GO, Brazil.

作者： Gustavo Almeida,Carvalho ^[1] ; Raphaela Almeida,Chiareli ^[1] ; Bruno Lemes,Marques ^[1] ; Ricardo Cambraia,Parreira ^[1] ; Eric,de Souza Gil ^[2] ; Flávio Silva,de Carvalho ^[2] ; André Luís Batista,da Rocha ^[2] ; Rafaela Ribeiro,Silva ^[3] ; François,Noël ^[3] ; Boniek Gontijo,Vaz ^[4] ; Luciano Morais,Lião ^[4] ; Shabir,Ahmad ^[5] ; Hugo,Verli ^[5] ; Ricardo,Menegatti ^[2] ; Mauro Cunha Xavier,Pinto ^[6]

作者单位： Department of Pharmacology, Federal University of Goias, Goiânia, GO, Brazil. ^[1] Faculty of Pharmacy, Federal University of Goias, Goiânia, GO, Brazil. ^[2] Department of Pharmacology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. ^[3] Institute of Chemistry, Federal University of Goias, Goiânia, GO, Brazil. ^[4] Center of Biotechnology, Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil. ^[5] Department of Pharmacology, Federal University of Goias, Goiânia, GO, Brazil. pintomcx@ufg.br.;Departamento de Farmacologia, Laboratório de Neuroquímica e Neurofarmacologia, Universidade Federal de Goiás, Instituto de Ciências Biológicas, Av. Esperança, S/N, UFG, Prédio ICB II, Sala 114, Goiânia, GO, 74690-900, Brazil. pintomcx@ufg.br. ^[6]

关键词 Glutamatergic neurotransmission Ischemia L-proline transporter SLC6A7 Stroke

医学主题词小鼠(Mice);动物(Animals);梗死, 大脑中动脉(Infarction, Middle Cerebral Artery);受体, N-甲基-D-天冬氨酸(Receptors, N-Methyl-D-Aspartate);脯氨酸(Proline);脑缺血(Brain Ischemia);疾病模型, 动物(Disease Models, Animal)

DOI 10.1007/s43440-023-00451-x

PMID 36719635

发布时间 2023-03-31

基金项目

88887.305550/2018-00/Fundação de Amparo à Pesquisa do Estado de Goiás 406765/2021-9/Conselho Nacional de Desenvolvimento Científico e Tecnológico 407075/2018-6/Conselho Nacional de Desenvolvimento Científico e Tecnológico 406048/2018-5/Conselho Nacional de Desenvolvimento Científico e Tecnológico APQ-00820-17/Fundação de Amparo à Pesquisa do Estado de Minas Gerais

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