Chemical mimetics of the N-degron pathway alleviate systemic inflammation by activating mitophagy and immunometabolic remodeling.

导出 OA

翻译打印收藏纠错

作者： Prashanta,Silwal ^[1] ; Young Jae,Kim ^[2] ; Yoon Jee,Lee ^[1] ; In Soo,Kim ^[2] ; Sang Min,Jeon ^[3] ; Taylor,Roh ^[4] ; Jin Kyung,Kim ^[1] ; Min Joung,Lee ^[2] ; Jun Young,Heo ^[3] ; Doo Sin,Jo ^[1] ; Sang-Hee,Lee ^[2] ; Dong-Hyung,Cho ^[3] ; Jin Man,Kim ^[1] ; Yong Tae,Kwon ^[2] ; Eun-Kyeong,Jo ^[3]

作者单位： Department of Microbiology, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea. ^[1] Infection Control Convergence Research Center, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea. ^[2] Department of Medical Science, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea. ^[3] Cellular Degradation Biology Center and Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, Republic of Korea. ^[4] Department of Microbiology, Keimyung University School of Medicine, Daegu, Republic of Korea. ^[5] Department of Biochemistry, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea. ^[6] School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea. ^[7] Bio-Electron Microscopy Research Center (104 Dong), Korea Basic Science Institute, Ochang, Cheongju, 28199, Republic of Korea. ^[8] Department of Pathology, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea. ^[9] Cellular Degradation Biology Center and Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, Republic of Korea. yok5@snu.ac.kr. ^[10] AUTOTAC Bio Inc., Changkyunggung-ro 254, Jongno-gu, Seoul, 03077, Republic of Korea. yok5@snu.ac.kr. ^[11] SNU Dementia Research Center, College of Medicine, Seoul National University, Seoul, 03080, Republic of Korea. yok5@snu.ac.kr. ^[12] Ischemic/Hypoxic Disease Institute and SNU Dementia Research Center, College of Medicine, Seoul National University, Seoul, 03080, Republic of Korea. yok5@snu.ac.kr. ^[13] Department of Microbiology, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea. hayoungj@cnu.ac.kr. ^[14] Infection Control Convergence Research Center, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea. hayoungj@cnu.ac.kr. ^[15] Department of Medical Science, Chungnam National University School of Medicine, Daejeon, 35015, Republic of Korea. hayoungj@cnu.ac.kr. ^[16]