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Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model.

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第一作者： A D,Roseborough

第一单位： Vulnerable Brain Laboratory, Department of Anatomy and Cell Biology, The Schulich School of Medicine and Dentistry, The University of Western Ontario, 458 Medical Sciences Building, ON, N6A 3K, London, Canada.

作者： A D,Roseborough ^[1] ; S J,Myers ^[1] ; R,Khazaee ^[2] ; Y,Zhu ^[1] ; L,Zhao ^[1] ; E,Iorio ^[3] ; F M,Elahi ^[4] ; S H,Pasternak ^[5] ; S N,Whitehead ^[6]

作者单位： Vulnerable Brain Laboratory, Department of Anatomy and Cell Biology, The Schulich School of Medicine and Dentistry, The University of Western Ontario, 458 Medical Sciences Building, ON, N6A 3K, London, Canada. ^[1] Biotron Integrated Microscopy Facility, The University of Western Ontario, London, ON, Canada.;Deparment of Biology, The University of Western Ontario, London, ON, Canada. ^[2] Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA. ^[3] Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.;Icahn School of Medicine at Mount Sinai, New York, USA.;Department of Clinical Neurological Sciences, The Schulich School of Medicine and Dentistry, The University of Western Ontario, ON, London, Canada. ^[4] Icahn School of Medicine at Mount Sinai, New York, USA.;Department of Clinical Neurological Sciences, The Schulich School of Medicine and Dentistry, The University of Western Ontario, ON, London, Canada.;Robarts Research Institute, The Schulich School of Medicine and Dentistry, The University of Western Ontario, ON, London, Canada. ^[5] Vulnerable Brain Laboratory, Department of Anatomy and Cell Biology, The Schulich School of Medicine and Dentistry, The University of Western Ontario, 458 Medical Sciences Building, ON, N6A 3K, London, Canada. shawn.whitehead@schulich.uwo.ca. ^[6]

关键词 Extracellular vesicle Microglia Stroke

医学主题词动物(Animals);大鼠(Rats);纹状体(Corpus Striatum);小神经胶质细胞(Microglia);表型(Phenotype);卒中(Stroke)

DOI 10.1186/s12974-023-02708-x

PMID 36721258

发布时间 2023-02-03

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