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Temporal evolution of new T1-weighted hypo-intense lesions and central brain atrophy in patients with a first clinical demyelinating event treated with subcutaneous interferon β-1a.

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作者: H,Vrenken [1] ; M,Battaglini [2] ; M L,de Vos [3] ; G J,Nagtegaal [3] ; B C A,Teixeira [4] ; A,Seitzinger [5] ; D,Jack [6] ; M P,Sormani [7] ; B M J,Uitdehaag [8] ; A,Versteeg [9] ; G,Comi [3] ; L,Kappos [10] ; N,De Stefano [11] ; F,Barkhof [12]
作者单位: Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands. H.Vrenken@amsterdamumc.nl. [1] Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy. [2] Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands. [3] Department of Radiology, Federal University of Paraná, Curitiba, Paraná, Brazil. [4] Neuroradiology Department, Neurological Institute of Curitiba (INC/CETAC), Curitiba, Paraná, Brazil. [5] Global Biostatistics, Merck Healthcare KGaA, Darmstadt, Germany. [6] Global Medical Affairs, Merck Serono Ltd, (an affiliate of Merck KGaA), Feltham, UK. [7] Department of Health Sciences, University of Genoa and Ospedale Policlinico San Martino IRCCS, Genoa, Italy. [8] Department of Neurology, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands. [9] Department of Radiology and Nuclear Medicine, Biomedical Imaging Group Rotterdam, Erasmus MC-University Medical Center Rotterdam, Rotterdam, The Netherlands. [10] Università Vita-Salute San Raffaele, Casa di Cura Privata del Policlinico, Milan, Italy. [11] Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB) and Neurology Departments of Head, Spine and Neuromedicine, Biomedical Engineering and Clinical Research, University Hospital, University of Basel, Basel, Switzerland. [12] UCL Institutes of Neurology and Healthcare Engineering, London, UK. [13]
DOI 10.1007/s00415-022-11554-5
PMID 36723685
发布时间 2023-03-28
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