The fibroblast growth factor receptor inhibitor, derazantinib, has strong efficacy in human gastric tumor models and synergizes with paclitaxel in vivo.
作者:
主题词
动物(Animals);人类(Humans);小鼠(Mice);细胞系, 肿瘤(Cell Line, Tumor);小鼠, 裸(Mice, Nude);紫杉酚(Paclitaxel);蛋白激酶抑制剂(Protein Kinase Inhibitors);受体, 成纤维细胞生长因子, 1型(Receptor, Fibroblast Growth Factor, Type 1);受体, 成纤维细胞生长因子(Receptors, Fibroblast Growth Factor);胃肿瘤(Stomach Neoplasms);肿瘤微环境(Tumor Microenvironment);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1097/CAD.0000000000001469
PMID
36729959
发布时间
2023-09-01
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Anti-cancer drugs
532-543页
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