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Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia.

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第一作者： Timothy,Johanssen

第一单位： Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

作者： Timothy,Johanssen ^[1] ; Laura,McVeigh ^[2] ; Sara,Erridge ^[3] ; Geoffrey,Higgins ^[4] ; Joelle,Straehla ^[5] ; Margaret,Frame ^[2] ; Tero,Aittokallio ^[6] ; Neil O,Carragher ^[2] ; Daniel,Ebner ^[7]

作者单位： Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom. ^[1] Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom. ^[2] Edinburgh Cancer Centre, Western General Hospital, Edinburgh, United Kingdom. ^[3] Department of Oncology, University of Oxford, Oxford, United Kingdom. ^[4] Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, United States. ^[5] Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.;Institute for Cancer Research, Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway.;Centre for Biostatistics and Epidemiology (OCBE), Faculty of Medicine, University of Oslo, Oslo, Norway. ^[6] Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.;Department of Oncology, University of Oxford, Oxford, United Kingdom. ^[7]

关键词 drug target combination glioblastoma glioblastoma stem cell high throughput screening (HTS)hypoxia radiotherapy temozolamide

DOI 10.3389/fonc.2022.1075559

PMID 36733367

发布时间 2025-05-30

基金项目

28596/CRUK_/Cancer Research UK/United Kingdom

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