换一批
换一批A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study.
作者：
Jesse J,Swen [1]
;
Cathelijne H,van der Wouden [1]
;
Lisanne En,Manson [1]
;
Heshu,Abdullah-Koolmees [2]
;
Kathrin,Blagec [3]
;
Tanja,Blagus [4]
;
Stefan,Böhringer [5]
;
Anne,Cambon-Thomsen [6]
;
Erika,Cecchin [7]
;
Ka-Chun,Cheung [8]
;
Vera Hm,Deneer [9]
;
Mathilde,Dupui [10]
;
Magnus,Ingelman-Sundberg [11]
;
Siv,Jonsson [12]
;
Candace,Joefield-Roka [13]
;
Katja S,Just [14]
;
Mats O,Karlsson [12]
;
Lidija,Konta [15]
;
Rudolf,Koopmann [16]
;
Marjolein,Kriek [17]
;
Thorsten,Lehr [18]
;
Christina,Mitropoulou [19]
;
Emmanuelle,Rial-Sebbag [20]
;
Victoria,Rollinson [21]
;
Rossana,Roncato [7]
;
Matthias,Samwald [3]
;
Elke,Schaeffeler [22]
;
Maria,Skokou [23]
;
Matthias,Schwab [24]
;
Daniela,Steinberger [16]
;
Julia C,Stingl [14]
;
Roman,Tremmel [25]
;
Richard M,Turner [21]
;
Mandy H,van Rhenen [8]
;
Cristina L,Dávila Fajardo [26]
;
Vita,Dolžan [4]
;
George P,Patrinos [27]
;
Munir,Pirmohamed [21]
;
Gere,Sunder-Plassmann [13]
;
Giuseppe,Toffoli [7]
;
Henk-Jan,Guchelaar [28]
;
Ubiquitous Pharmacogenomics Consortium
作者单位：
Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, Netherlands.
[1]
Division Laboratories, Pharmacy and Biomedical Genetics, Hospital Pharmacy, University Medical Centre Utrecht, Utrecht, Netherlands.
[2]
Centre for Medical Statistics, Informatics and Intelligent Systems, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria.
[3]
Pharmacogenetics Laboratory, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
[4]
Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, Netherlands; Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, Netherlands.
[5]
CNRS, Centre for Epidemiology and Research in Population health (CERPOP), Université de Toulouse, Inserm, UPS, Toulouse, France.
[6]
Experimental and Clinical Pharmacology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
[7]
Medicines Information Centre, Royal Dutch Pharmacists Association (KNMP), The Hague, Netherlands.
[8]
Division Laboratories, Pharmacy and Biomedical Genetics, Hospital Pharmacy, University Medical Centre Utrecht, Utrecht, Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Netherlands.
[9]
Service de pharmacologie médicale et clinique, CEIP-addictovigilance de Toulouse, faculté de médecine, CHU, Toulouse, France.
[10]
Department of Physiology and Pharmacology, Karolinska Institutet, Biomedicum, Stockholm, Sweden.
[11]
Department of Pharmacy, Uppsala University, Uppsala, Sweden.
[12]
Department of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
[13]
Institute of Clinical Pharmacology, University Hospital RWTH Aachen, Aachen, Germany.
[14]
Bio.logis Digital Health, Frankfurt am Main, Germany.
[15]
Bio.logis Digital Health, Frankfurt am Main, Germany; Diagnosticum Centre for Humangenetics, Frankfurt am Main, Germany.
[16]
Department of Clinical Genetics, Leiden University Medical Centre, Leiden, Netherlands.
[17]
Clinical Pharmacy, Saarland University, Saarbrücken, Germany.
[18]
The Golden Helix Foundation, London, UK; Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, Abu Dhabi, United Arab Emirates.
[19]
Universite de Toulouse III Paul Sabatier, Toulouse, France.
[20]
Department of Pharmacology and Therapeutics, Wolfson Centre for Personalised Medicine, The University of Liverpool, Liverpool, UK.
[21]
Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; iFIT Cluster of Excellence (EXC2180)-Image Guided and Functionally Instructed Tumour Therapies, University of Tuebingen, Tuebingen, Germany.
[22]
University of Patras School of Health Sciences, Department of Pharmacy, Division of Pharmacology and Biosciences, Laboratory of Pharmacogenomics and Individualised Therapy, Patras, Greece.
[23]
Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; iFIT Cluster of Excellence (EXC2180)-Image Guided and Functionally Instructed Tumour Therapies, University of Tuebingen, Tuebingen, Germany; Department of Clinical Pharmacology, University of Tuebingen, Tuebingen, Germany; Department of Pharmacy and Biochemistry, University of Tuebingen, Tuebingen, Germany.
[24]
Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.
[25]
Clinical Pharmacy Department, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria Granada, Granada, Spain.
[26]
Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, Abu Dhabi, United Arab Emirates; Zayed Centre for Health Sciences, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, Abu Dhabi, United Arab Emirates; University of Patras School of Health Sciences, Department of Pharmacy, Division of Pharmacology and Biosciences, Laboratory of Pharmacogenomics and Individualised Therapy, Patras, Greece; Erasmus University Medical Centre, Faculty of Medicine and Health Sciences, Department of Pathology-Clinical Bioinformatics Unit, Rotterdam, Netherlands.
[27]
Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, Netherlands. Electronic address: h.j.guchelaar@lumc.nl.
[28]
主题词
人类(Humans);男(雄)性(Male);女(雌)性(Female);遗传药理学(Pharmacogenetics);基因检测(Genetic Testing);基因型(Genotype);复方合剂(Drug Combinations);治疗结果(Treatment Outcome)
DOI
10.1016/S0140-6736(22)01841-4
PMID
36739136
发布时间
2024-01-23
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Lancet (London, England)
Lancet (London, England)
347-356页
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